

It is recognized by a relentless pursuit for thinness, extreme low body weight, and is often accompanied by a disturbed body image and a denial of illness. Anorexia nervosa (AN) is a severe eating disorder, with the highest mortality rate of any mental illness. This could contribute to the development of better and more targeted treatment strategies.Įating disorders are characterized by a persistent disturbance of eating or eating-related behaviour that result in altered consumption of food, which significantly impairs physical health or psychosocial functioning. A complete understanding of predisposing, precipitating and maintaining factors in AN needs to be addressed in future research. Conclusionsįindings indicate that BMI, depression and anxiety does not influence neuropsychological function in AN, suggesting that it could be a characteristic of the disorder. ResultsĪlthough results are heterogeneous, the majority of studies report that neither body mass index (BMI), anxiety or depression is associated with altered central coherence and set-shifting in individuals with AN. Results were summarized in a narrative synthesis.

Risk of bias was assessed by using a critical appraisal checklist from the Joanna Briggs Institute. Studies were included if they were written in English, peer-reviewed, included individuals with AN, included tests measuring set-shifting and/or central coherence, investigated associations between set-shifting/central coherence with anxiety and/or depression and/or BMI. Literature was identified via searches in PubMed, PsychInfo and Embase database, by using the search words AND, and AND. MethodĪ systematic review approach was used, following the PRISMA guidelines for systematic reviews. The aim of this review was to evaluate whether neuropsychological impairments in AN are influenced by body mass index, anxiety or depression. The disorder is often accompanied by comorbid disorders such as anxiety and depression, and altered neuropsychological function in terms of poor set-shifting and reduced central coherence.

Anorexia nervosa (AN) is a severe eating disorder, recognized by a relentless pursuit for thinness and extreme low body weight.
